From 745ec03e43db6fab6361221f61443f7ef6859470 Mon Sep 17 00:00:00 2001 From: BikerDuality <22326595+BikerDuality@users.noreply.github.com> Date: Fri, 5 Nov 2021 17:14:21 +0800 Subject: [PATCH] =?UTF-8?q?=E6=B7=BB=E5=8A=A0=E8=89=B2=E6=99=AE=E9=BE=99?= =?UTF-8?q?=E8=AF=B1=E5=8F=91=E8=84=91=E8=86=9C=E7=98=A4=E9=A3=8E=E9=99=A9?= =?UTF-8?q?=E8=AD=A6=E5=91=8A=20(#173)?= MIME-Version: 1.0 Content-Type: text/plain; charset=UTF-8 Content-Transfer-Encoding: 8bit * 添加色普龙诱发脑膜瘤风险警告 * Words edited for accuracy Co-authored-by: Rinfair --- content/zh-cn/docs/medicine/HRT.md | 1 + content/zh-cn/docs/medicine/antiandrogen/cyproterone.md | 3 +++ 2 files changed, 4 insertions(+) diff --git a/content/zh-cn/docs/medicine/HRT.md b/content/zh-cn/docs/medicine/HRT.md index bbf3eafd..b693f3d1 100644 --- a/content/zh-cn/docs/medicine/HRT.md +++ b/content/zh-cn/docs/medicine/HRT.md @@ -95,6 +95,7 @@ weight: 1 - 孕激素对于 MtF 没有确切的女性化效果。 - 在抗雄用量下，色普龙（醋酸环丙孕酮）有极强的合成孕激素作用 +- 色普龙（醋酸环丙孕酮）有诱发脑膜瘤的风险 - 过早引入孕激素可能抑制乳房发育（未证实） ## HRT 效果参考 diff --git a/content/zh-cn/docs/medicine/antiandrogen/cyproterone.md b/content/zh-cn/docs/medicine/antiandrogen/cyproterone.md index 988ee9d4..ad370397 100644 --- a/content/zh-cn/docs/medicine/antiandrogen/cyproterone.md +++ b/content/zh-cn/docs/medicine/antiandrogen/cyproterone.md @@ -84,6 +84,8 @@ weight: 1 ## 副作用 +- **脑膜瘤风险**：色谱龙可能诱发脑膜瘤，风险与剂量和使用时长正相关，建议谨慎使用。[^6] + - **抑郁**：色普龙会导致抑郁风险升高[^2]。主要原因是色普龙对于生理男性起到了抗雄激素和潜在的糖皮质激素作用，并可能诱发维生素 B12 缺乏[^3]。有必要适量补充维生素 B12 ． - **肝毒性**：色普龙最严重的副作用，使用前应当检查肝功能并定期检查，服用量不应当超过 50mg[^4]． @@ -105,3 +107,4 @@ weight: 1 [^3]: [Clinical and experimental dermatology. Supplement ... : CED.](https://www.worldcat.org/title/clinical-and-experimental-dermatology-supplement-ced/oclc/499941040) [^4]: [PRODUCT MONOGRAPH](https://web.archive.org/web/20060924152720/http://www.berlex.ca/html/docs/en/AndrocurEn.pdf) [^5]: [醋酸环丙孕酮片](http://yao.dxy.com/drug/132923.htm) +[^6]: [法国关于醋酸环丙孕酮和脑膜瘤风险的研究的最新进展以及对女性倾向跨性别者的影响](https://limelight.moe/t/topic/8313)